Health Top Stories

Treating Gum Disease Linked to Lower Medical Costs for Patients with Diabetes

A new report suggests that treating gum disease in patients who have diabetes with procedures such as cleanings and periodontal scaling is linked to 10 to 12 percent lower medical costs per month. The findings are encouraging but the study was not designed to firmly establish cause and effect, said George Taylor, University of Michigan associate professor of dentistry, who also has an appointment in epidemiology in the U-M School of Public Health. Taylor led the research project to investigate whether routine, non-surgical treatment for gum disease is linked to lower medical care costs for people with diabetes. In periodontal disease, the body reacts to the bacteria causing the gum infection by producing proteins or chemicals called inflammatory mediators. Ulcers and open sores in the gums become passageways for these proteins and for the bacteria themselves to enter the body?s blood circulation. These inflammatory mediators, as well as some parts of the bacteria, prevent the body from effectively removing glucose, or sugar, from the blood.  More »

Obese siblings of diabetic children at risk

Compared with other overweight children, overweight siblings of children with type 2 diabetes mellitus have a significantly higher prevalence of abnormal glucose tolerance, a risk factor for diabetes, according to researchers at the Children?s Hospital of Philadelphia. ?These siblings,? lead investigator Dr. Sheela N. Magge told Reuters Health, ?have a unique combination of genetic and environmental risk factors. We found that the obese sibling group had four-times higher odds of having abnormal glucose tolerance?pre-diabetes and diabetes?compared to the control group.? Magge and colleagues studied 62 obese children, aged 8 to 17 years, who had at least 1 sibling aged 12 years or older. Twenty children had a sibling with diabetes; 42 acted as controls, according to the study, published in the Journal of Pediatrics. More »

Using math to understand hepatitis C

Using math to understand hep. C: Patterns paint picture of who will respond to treatment Genetic patterns are like the tea leaves in the bottom of a cup for predicting which patients are likely to respond to medical therapy for life-threatening viruses such as hepatitis C, Saint Louis University researchers have discovered. Their findings are published in the Dec. 22 early online issue of the Journal of Clinical Investigation. ?We identified mathematical patterns, which are called ?covariance networks,? to analyze the sequence of proteins in the genes or ?genetic patterns? of hepatitis C virus in two groups of patients ? those who responded to and those who resisted traditional therapy,? said John Tavis, Ph.D., professor of molecular and microbiology at Saint Louis University and a lead author of the paper. ?What we found will allow a doctor to predict whether or not a medication will work in a patient.? More »